Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057459 | 0.95 | CHRM2 (0.45) | L3MBTL1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9058004 | 0.87 | ALDH1A1 (0.39) | L3MBTL1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9058947 | 0.85 | HRH3 (0.43) | L3MBTL1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9057843 | 0.84 | MC4R (0.40) | L3MBTL1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9057546 | 0.82 | HRH3 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12814048 | 0.80 | ALDH1A1 (0.54) | L3MBTL1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9057438 | 0.79 | HCRTR1 (0.43) | ALDH1A1LMNA | |
| SCHEMBL9057980 | 0.79 | HCRTR1 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9074197 | 0.77 | ALDH1A1 (0.61) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10588007 | 0.76 | ALDH1A1 (0.57) | L3MBTL1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017862-A1 | LHRH ANTAGONISTS HAVING LACTAM GROUPS AT THE N-TERMINUS | ABBOTT LABORATORIES (US) | 1996-06-13 | — | — | WO | disclosed |
| US-5516759-A | LHRH antagonists having lactam groups at the N-terminus | TAP HOLDINGS INC. (US) | 1996-05-14 | — | — | US | disclosed |