Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057516 | 0.96 | SLC6A4 (0.39) | HCRTR1HCRTR2SLC6A4CTNNB1KCNA5 | |
| SCHEMBL9070230 | 0.79 | CTNNB1 (0.45) | SLC6A4CTNNB1CHRM2CHRM4CHRM5 | |
| SCHEMBL9059652 | 0.79 | L3MBTL1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9058947 | 0.79 | HRH3 (0.43) | HCRTR1HCRTR2SLC6A4CHRM2CHRM4 | |
| SCHEMBL9057546 | 0.76 | HRH3 (0.40) | HCRTR1HCRTR2SLC6A4CHRM2CHRM4 | |
| SCHEMBL9073483 | 0.75 | CTNNB1 (0.46) | SLC6A4CTNNB1CHRM2CHRM4CHRM5 | |
| SCHEMBL9057459 | 0.74 | CHRM2 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10763341 | 0.73 | CTNNB1 (0.42) | SLC6A4CTNNB1MEN1KMT2A | |
| SCHEMBL9057438 | 0.73 | HCRTR1 (0.43) | HCRTR1HCRTR2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9058004 | 0.72 | ALDH1A1 (0.39) | SLC6A4CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017862-A1 | LHRH ANTAGONISTS HAVING LACTAM GROUPS AT THE N-TERMINUS | ABBOTT LABORATORIES (US) | 1996-06-13 | — | — | WO | disclosed |
| US-5516759-A | LHRH antagonists having lactam groups at the N-terminus | TAP HOLDINGS INC. (US) | 1996-05-14 | — | — | US | disclosed |