Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057546 | 0.97 | HRH3 (0.40) | HRH3HTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL9059652 | 0.85 | L3MBTL1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9057438 | 0.83 | HCRTR1 (0.43) | DPP4HCRTR1HCRTR2ITGB2ICAM1 | |
| SCHEMBL9057459 | 0.81 | CHRM2 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9057848 | 0.80 | HCRTR1 (0.42) | DPP4HCRTR1HCRTR2ITGB2ICAM1 | |
| SCHEMBL9058004 | 0.79 | ALDH1A1 (0.39) | HRH3SLC6A4DPP4CHRM2CHRM4 | |
| SCHEMBL9057980 | 0.79 | HCRTR1 (0.39) | SLC6A4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9058043 | 0.77 | MEN1 (0.53) | SLC6A4DPP4KMT2AITGB2ICAM1 | |
| SCHEMBL9057843 | 0.76 | MC4R (0.40) | SLC6A4DPP4CHRM2CHRM4CHRM5 | |
| SCHEMBL9057516 | 0.74 | SLC6A4 (0.39) | SLC6A4CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017862-A1 | LHRH ANTAGONISTS HAVING LACTAM GROUPS AT THE N-TERMINUS | ABBOTT LABORATORIES (US) | 1996-06-13 | — | — | WO | claimed |
| US-5516759-A | LHRH antagonists having lactam groups at the N-terminus | TAP HOLDINGS INC. (US) | 1996-05-14 | — | — | US | claimed |
| WO-1996017862-A1 | LHRH ANTAGONISTS HAVING LACTAM GROUPS AT THE N-TERMINUS | ABBOTT LABORATORIES (US) | 1996-06-13 | — | — | WO | disclosed |
| US-5516759-A | LHRH antagonists having lactam groups at the N-terminus | TAP HOLDINGS INC. (US) | 1996-05-14 | — | — | US | disclosed |