Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HINT1 | P49773 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003285 | 0.86 | POLB (0.51) | TAAR1POLBHINT1PNPP2RY2 | |
| SCHEMBL9294597 | 0.83 | TYMP (0.46) | TAAR1POLBHINT1P2RY2P2RY4 | |
| SCHEMBL7999683 | 0.83 | POLB (0.45) | TAAR1POLBHINT1PNPP2RY2 | |
| SCHEMBL718291 | 0.83 | POLB (0.48) | TAAR1POLBHINT1PNPP2RY2 | |
| SCHEMBL6835146 | 0.83 | TYMP (0.45) | TAAR1POLBHINT1P2RY2P2RY4 | |
| SCHEMBL5355319 | 0.82 | POLB (0.47) | TAAR1POLBHINT1PNPP2RY2 | |
| SCHEMBL5360855 | 0.79 | POLB (0.62) | TAAR1POLBHINT1PNPP2RY2 | |
| SCHEMBL3779342 | 0.79 | POLB (0.55) | TAAR1POLBHINT1PNPP2RY2 | |
| SCHEMBL30712246 | 0.78 | POLB (0.58) | POLBPNPP2RY2P2RY4P2RY6 | |
| SCHEMBL29546691 | 0.77 | POLB (0.57) | POLBPNPP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490281-B1 | 3'- Amino or thiolmodified, fluorescence coupled nucleoside and oligonucleotide, a method for their preparation and their use | HOECHST AG (DE) | 1996-09-04 | — | — | EP | disclosed |
| EP-0490281-A1 | 3'- Amino or thiolmodified, fluorescence coupled nucleoside and oligonucleotide, a method for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |