Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 3/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718291 | 0.92 | POLB (0.48) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL9059968 | 0.86 | TAAR1 (0.49) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL5355319 | 0.84 | POLB (0.47) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL3779342 | 0.83 | POLB (0.55) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL30712246 | 0.83 | POLB (0.58) | POLBP2RY2P2RY4P2RY6STING1 | |
| SCHEMBL29546691 | 0.82 | POLB (0.57) | POLBP2RY2P2RY4P2RY6STING1 | |
| SCHEMBL6835146 | 0.82 | TYMP (0.45) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL3503649 | 0.81 | POLB (0.56) | POLBP2RY2P2RY4P2RY6STING1 | |
| SCHEMBL9294597 | 0.81 | TYMP (0.46) | POLBP2RY2P2RY4P2RY6HINT1 | |
| SCHEMBL7999683 | 0.81 | POLB (0.45) | POLBP2RY2P2RY4P2RY6HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018778-A9 | SYNTHESIS OF CODON RANDOMIZED NUCLEIC ACIDS | PHYLOS INC (US) | 2000-06-08 | — | — | WO | disclosed |