Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732869 | 0.85 | XDH (0.46) | XDHPOLA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7809880 | 0.82 | XDH (0.61) | XDHPOLA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6272728 | 0.79 | PNP (0.58) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8522269 | 0.75 | PNP (0.56) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL7777164 | 0.73 | PNP (0.54) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL6272296 | 0.73 | PNP (0.54) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL8536005 | 0.73 | PNP (0.54) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL65614 | 0.73 | GDA (0.40) | XDHPNP | |
| Hydrochloric Acid SCHEMBL258896 | 0.72 | PNP (0.53) | PI4KAPI4K2BPI4K2API4KBGPR84 | |
| SCHEMBL6233162 | 0.72 | XDH (0.51) | XDHPARP1ALDH1A1MAPK1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206593-B2 | Adapted for on-chip solvent exchange; synthesis of radiopharmaceuticals such as FDG (fludeoxyglucose F18) for example | FLUIDIGM CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| WO-1996022098-A1 | USE OF ACYCLIC PURINE DERIVATIVES FOR TREATING RESTENOSIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-25 | — | — | WO | disclosed |