Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.55 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809886 | 0.84 | XDH (0.57) | XDHPOLA1PNPHTTNCOA1 | |
| SCHEMBL2732874 | 0.83 | XDH (0.52) | XDHPOLA1PNPHTTNCOA1 | |
| SCHEMBL27762591 | 0.81 | XDH (0.50) | XDHPOLA1PNPHTTNCOA1 | |
| SCHEMBL27617650 | 0.80 | POLA1 (0.45) | POLA1PNPPDE5AALDH1A1GRIA1 | |
| SCHEMBL595204 | 0.79 | PNP (0.57) | XDHPNPGDAALDH1A1GRIA1 | |
| Hydrochloric Acid SCHEMBL17186227 | 0.78 | PNP (0.56) | XDHPNPGDAALDH1A1GRIA1 | |
| Hydrochloric Acid SCHEMBL17186358 | 0.78 | PNP (0.56) | XDHPNPGDAALDH1A1GRIA1 | |
| SCHEMBL5133747 | 0.77 | PDE5A (0.51) | XDHPOLA1PNPPDE5AGDA | |
| SCHEMBL9275484 | 0.77 | PNP (0.48) | XDHPOLA1PNPPDE5AGDA | |
| SCHEMBL27718742 | 0.76 | PDE9A (0.51) | PNPPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206593-B2 | Adapted for on-chip solvent exchange; synthesis of radiopharmaceuticals such as FDG (fludeoxyglucose F18) for example | FLUIDIGM CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| WO-1996022098-A1 | USE OF ACYCLIC PURINE DERIVATIVES FOR TREATING RESTENOSIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-25 | — | — | WO | disclosed |