Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL9060237

CNC(C)(C)C.O=C(O)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
CA2 P00918 1/20 0.35
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28336879 0.84 CA2 (0.47) ALDH1A1TSHRCA2L3MBTL1THRB
Trifluoroacetic Acid SCHEMBL2435717 0.84 CA2 (0.40) ALDH1A1TSHRCA2L3MBTL1THRB
Trifluoroacetic Acid SCHEMBL30872779 0.83 ALDH1A1 (0.36) ALDH1A1TSHRCA2NOS1NOS2
Trifluoroacetic Acid SCHEMBL6576795 0.80 ALDH1A1 (0.38) ALDH1A1TSHRCA2CYP2D6CYP2C19
Trifluoroacetic Acid SCHEMBL28224030 0.79 CA2 (0.36) ALDH1A1TSHRCA2L3MBTL1NOS1
Trifluoroacetic Acid SCHEMBL6222069 0.79 CA2 (0.36) ALDH1A1TSHRCA2L3MBTL1THRB
Trifluoroacetic Acid SCHEMBL28996861 0.79 CA2 (0.36) ALDH1A1TSHRCA2L3MBTL1THRB
Trifluoroacetic Acid SCHEMBL31050235 0.79 CA2 (0.36) ALDH1A1TSHRCA2L3MBTL1NOS1
Pivalate SCHEMBL30235549 0.78 ALDH1A1 (0.47) ALDH1A1TSHRCA2CYP2D6CYP2C19
Trifluoroacetic Acid SCHEMBL2455122 0.78 ALDH1A1 (0.56) ALDH1A1TSHRCA2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996012506-A1 SENESCENT CELL-DERIVED INHIBITORS OF DNA SYNTHESIS BAYLOR COLLEGE OF MEDECINE (US) 1996-05-02 WO disclosed