Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28224030

CNN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36
ALDH1A1 P00352 4/20 0.35
TSHR P16473 3/20 0.35
CHIT1 Q13231 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
DGAT1 O75907 1/20 0.32
THRB P10828 1/20 0.32
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FUCA1 P04066 1/20 0.30
CYP1A2 P05177 1/20 0.30
NFKB1 P19838 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31050235 1.00 CA2 (0.36) CA2ALDH1A1TSHRCHIT1L3MBTL1
Trifluoroacetic Acid SCHEMBL2435717 0.87 CA2 (0.40) CA2ALDH1A1TSHRCHIT1L3MBTL1
Trifluoroacetic Acid SCHEMBL28336879 0.87 CA2 (0.47) CA2ALDH1A1TSHRCHIT1L3MBTL1
Trifluoroacetic Acid SCHEMBL1731636 0.83
Trifluoroacetic Acid SCHEMBL29615579 0.83 ALDH1A1 (0.41) CA2ALDH1A1TSHRL3MBTL1NOS1
Trifluoroacetic Acid SCHEMBL10587540 0.82 DGAT1 (0.34) CA2ALDH1A1TSHRL3MBTL1NOS1
Trifluoroacetic Acid SCHEMBL6576795 0.82 ALDH1A1 (0.38) CA2ALDH1A1TSHRL3MBTL1NOS1
Trifluoroacetic Acid SCHEMBL29695879 0.82 CHIT1 (0.38) CA2TSHRCHIT1NOS1NOS2
Trifluoroacetic Acid SCHEMBL6222069 0.81 CA2 (0.36) CA2ALDH1A1TSHRCHIT1L3MBTL1
Trifluoroacetic Acid SCHEMBL28996861 0.81 CA2 (0.36) CA2ALDH1A1TSHRCHIT1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108129357-A The preparation method of anamorelin intermediate 上海医药工业研究院 2018-06-08 CN disclosed