SCHEMBL9060375

SCHEMBL9060375

Cc1ccccc1NC(O)=S

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
HPGD P15428 5/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
KDM4E B2RXH2 1/20 0.58
HTT P42858 1/20 0.58
ALDH1A1 P00352 4/20 0.57
POLB P06746 2/20 0.57
EPHX1 P07099 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.55
LMNA P02545 2/20 0.54
ALOX12 P18054 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
CYP2C19 P33261 1/20 0.53
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1285897 0.94 POLB (0.56) NPC1RAB9AHPGDSMN1; SMN2KDM4E
Selenium SCHEMBL11702079 0.92 POLB (0.55) NPC1RAB9AHPGDSMN1; SMN2KDM4E
Ethane SCHEMBL1054600 0.92 POLB (0.55) NPC1RAB9AHPGDSMN1; SMN2KDM4E
SCHEMBL9359399 0.92 POLB (0.55) NPC1RAB9AHPGDSMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL11776275 0.92 POLB (0.55) NPC1RAB9AHPGDSMN1; SMN2KDM4E
SCHEMBL9355942 0.92 POLB (0.55) NPC1RAB9AHPGDSMN1; SMN2KDM4E
Trimethylammonium SCHEMBL11773079 0.87 ALDH1A1 (0.50) NPC1RAB9AHPGDSMN1; SMN2KDM4E
SCHEMBL29522293 0.84 L3MBTL1 (0.70) NPC1RAB9AHPGDSMN1; SMN2KDM4E
SCHEMBL1276741 0.84 L3MBTL1 (0.70) NPC1RAB9AHPGDSMN1; SMN2KDM4E
SCHEMBL28146972 0.83 ALDH1A1 (0.48) NPC1RAB9AHPGDSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54041818-A None JP disclosed
JP-8301841-A None JP disclosed
CN-111320562-B Method for producing isothiocyanate 旭化成株式会社 2022-08-16 CN disclosed
CN-113880741-A Method for producing isothiocyanate 旭化成株式会社 2022-01-04 CN disclosed
CN-111320562-A Method for producing isothiocyanate 旭化成株式会社 2020-06-23 CN disclosed
JP-H08301841-A SQUALENE-EPOXYDASE ACTIVITY INHIBITOR GREEN CROSS CORP:THE 1996-11-19 JP disclosed
JP-S5441818-A PREPARATION OF ISOCYANATE COMPOUND UNITIKA LTD 1979-04-03 JP disclosed
US-4042641-A Inhibiting premature vulcanization of rubbers with N-aryl-hydrocarbyldithio-formimidate THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-08-16 US disclosed