Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014284 | 0.83 | MAOA (0.52) | MAOAMAOBLMNARXFP1MEN1 | |
| SCHEMBL7017363 | 0.82 | MAOA (0.46) | MAOAMAOBLMNARXFP1MEN1 | |
| SCHEMBL7018169 | 0.82 | KDM4E (0.57) | MAOAMAOBLMNAMEN1KMT2A | |
| SCHEMBL7011339 | 0.82 | MAOA (0.46) | MAOAMAOBLMNARXFP1MEN1 | |
| SCHEMBL7013210 | 0.81 | MEN1 (0.53) | MAOAMAOBLMNAMEN1KMT2A | |
| SCHEMBL7015339 | 0.81 | KMT2A (0.68) | LMNAMEN1KMT2AMAPTTP53 | |
| SCHEMBL7019775 | 0.81 | MEN1 (0.58) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL7012234 | 0.81 | MEN1 (0.50) | MAOAMAOBLMNARXFP1MEN1 | |
| SCHEMBL7011263 | 0.81 | MAOA (0.52) | MAOAMAOBLMNARXFP1MEN1 | |
| SCHEMBL7018370 | 0.81 | MEN1 (0.50) | MAOAMAOBLMNARXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8311041-A | — | — | None | — | — | JP | disclosed |
| JP-H08311041-A | HETEROCYCLIC COMPOUND AND PREPARATION THEREFROM | TAKEDA CHEM IND LTD | 1996-11-26 | — | — | JP | disclosed |