SCHEMBL9060774

SCHEMBL9060774

C=CC(=O)OC1(C(=O)OCCCC)CC2CCC1C2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
HPGD P15428 1/20 0.46
ATM Q13315 1/20 0.38
HCAR2 Q8TDS4 3/20 0.35
LMNA P02545 3/20 0.33
HTT P42858 3/20 0.33
THRB P10828 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.33
EPHX2 P34913 4/20 0.32
MAPT P10636 3/20 0.32
NPSR1 Q6W5P4 3/20 0.32
RAB9A P51151 1/20 0.32
PLA2G1B P04054 1/20 0.30
MAPK1 P28482 1/20 0.30
RAD52 P43351 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL655346 0.78
SCHEMBL27562595 0.77 LMNA (0.37) TSHRHPGDATMLMNAHTT
SCHEMBL650899 0.76 HSD11B1 (0.31)
SCHEMBL4400965 0.75 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL11407106 0.74 ATM (0.36) TSHRHPGDATMHCAR2LMNA
SCHEMBL27646654 0.73 TSHR (0.44) TSHRHPGDATMHCAR2LMNA
SCHEMBL4401909 0.72 HPGD (0.32) TSHRHPGDTHRB
SCHEMBL4401644 0.71 HPGD (0.30) TSHRHPGD
SCHEMBL9060780 0.71 TSHR (0.44) TSHRHPGDATMHCAR2THRB
SCHEMBL9060777 0.71 TSHR (0.44) TSHRHPGDATMHCAR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8333304-A None JP disclosed
JP-H08333304-A ALKOXYCARBONYLNORBORNYL (METH)ACRYLATE, ITS PRODUCTION AND PHOTOSENSITIVE RESIN COMPOSITION IDEMITSU PETROCHEM CO LTD 1996-12-17 JP disclosed