Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 12/20 | 0.63 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | GCK | P35557 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82675 | 0.91 | HCAR3 (0.68) | HCAR3PTK2HCAR2 | |
| Toluene SCHEMBL27348422 | 0.88 | PTK2 (0.53) | HCAR3PTK2NSD2TP53TSHR | |
| SCHEMBL27343709 | 0.87 | KDM4E (0.62) | HCAR3PTK2HCAR2GCKTP53 | |
| Pyridine SCHEMBL5437479 | 0.85 | HCAR3 (0.59) | HCAR3PTK2NSD2HCAR2 | |
| SCHEMBL27347169 | 0.83 | HCAR3 (0.55) | HCAR3PTK2HCAR2 | |
| SCHEMBL27335268 | 0.82 | HCAR3 (0.52) | HCAR3PTK2NSD2HCAR2RAB9A | |
| SCHEMBL27349315 | 0.82 | HCAR3 (0.50) | HCAR3PTK2NSD2HCAR2GCK | |
| SCHEMBL27347795 | 0.82 | HCAR3 (0.52) | HCAR3PTK2NSD2HCAR2RAB9A | |
| SCHEMBL7093993 | 0.79 | PTK2 (0.62) | HCAR3PTK2NSD2TP53TSHR | |
| SCHEMBL28118455 | 0.78 | PTK2 (0.54) | HCAR3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1198746-A | Tricyclic benzazepine * vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-11-11 | — | — | CN | disclosed |
| WO-1996022295-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |