Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462425 | 0.90 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL13324861 | 0.90 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL26661473 | 0.86 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL13324859 | 0.82 | HTR2A (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11593080 | 0.82 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL30010692 | 0.81 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL9062019 | 0.81 | LMNA (0.49) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL27610152 | 0.81 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL11012775 | 0.80 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL3122029 | 0.80 | MAOB (0.52) | SMN1; SMN2ALDH1A1HPGDL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482867-A | Spatially-addressable immobilization of anti-ligands on surfaces | AFFYMAX TECHNOLOGIES N.V. (NL) | 1996-01-09 | — | — | US | disclosed |
| US-5451683-A | Spatially-addressable immobilization of anti-ligands on surfaces | AFFYMAX TECHNOLOGIES N.V. | 1995-09-19 | — | — | US | disclosed |
| US-5252743-A | Using cage binding compound | AFFYMAX TECHNOLOGIES N.V. (NL) | 1993-10-12 | — | — | US | disclosed |
| EP-0502060-A4 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0502060-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991007087-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1991-05-30 | — | — | WO | disclosed |