Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062110 | 1.00 | MDM4 (0.58) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL17316186 | 0.94 | MDM2 (0.54) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL29400804 | 0.92 | FDFT1 (0.57) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL29762010 | 0.92 | FDFT1 (0.57) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL29768618 | 0.92 | FDFT1 (0.57) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL4600701 | 0.92 | FDFT1 (0.57) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL800305 | 0.92 | FDFT1 (0.57) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL800035 | 0.92 | FDFT1 (0.57) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL29362132 | 0.92 | FDFT1 (0.57) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL30777648 | 0.91 | MDM4 (0.54) | MDM4TP53MDM2CASP3TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545568-A | ARRAY OF COMPOUNDS ON SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1994006291-A1 | SOLID PHASE AND COMBINATORIAL SYNTHESIS OF COMPOUNDS ON A SOLID SUPPORT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-31 | — | — | WO | disclosed |