Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730662 | 0.86 | EPHX1 (0.46) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL11096635 | 0.85 | CTSK (0.46) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL9220692 | 0.85 | HDAC4 (0.43) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL10403877 | 0.85 | CTSS (0.49) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL11272866 | 0.85 | CTSS (0.49) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL15486809 | 0.85 | HDAC4 (0.48) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL27412802 | 0.85 | HDAC4 (0.48) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL15563297 | 0.85 | HDAC4 (0.48) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL9099322 | 0.83 | CTSK (0.55) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL7296839 | 0.83 | CTSK (0.58) | CTSKHDAC4HDAC1HDAC6CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717040-A1 | Thiazine or thiazepine derivatives which inhibit NOS | Japan Tobacco Inc. (JP) | 1996-06-19 | — | — | EP | disclosed |