Xanthopterin

Xanthopterin

SCHEMBL906220

Nc1nc(O)c2nc(O)cnc2n1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 7/20 0.46
ADORA2A P29274 1/20 0.44
PIK3CA P42336 1/20 0.42
PIK3CB P42338 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
DHFR P00374 1/20 0.35
NOS1 P29475 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthopterin SCHEMBL6475885 0.98 PIK3CG (0.45) PIK3CGADORA2APIK3CAPIK3CBHDAC6
Isoxanthopterin SCHEMBL4389432 0.84 PIK3CG (0.46) PIK3CGADORA2APIK3CAPIK3CBHDAC6
SCHEMBL24629319 0.84 PIK3CG (0.42) PIK3CGADORA2APIK3CAPIK3CBHDAC6
SCHEMBL6239850 0.81 PIK3CG (0.41) PIK3CGADORA2APIK3CAPIK3CBHDAC6
SCHEMBL16023555 0.78 NOS1 (0.40) PIK3CGDHFRNOS1
SCHEMBL15075219 0.77 NOS1 (0.45) DHFRNOS1
Pterin-6-Carboxylic Acid SCHEMBL31438602 0.77 DHFR (0.45) PIK3CGADORA2APIK3CAPIK3CBHDAC6
Pterin-6-Carboxylic Acid SCHEMBL13820952 0.77 DHFR (0.45) PIK3CGADORA2APIK3CAPIK3CBHDAC6
SCHEMBL27955370 0.77 NOS1 (0.39) PIK3CGADORA2ADHFRNOS1
SCHEMBL23270838 0.77 PIK3CG (0.38) PIK3CGADORA2APIK3CAPIK3CBHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473287-B2 Synthetic co-crystals of anhydrous guanine and process for preparing the same ECOCRYSTAL LTD. (IL) 2025-11-18 US claimed
US-20240208977-A1 SYNTHETIC CO-CRYSTALS OF ANHYDROUS GUANINE AND PROCESS FOR PREPARING THE SAME ECOCRYSTAL LTD. (IL) 2024-06-27 US claimed
US-11858936-B2 Synthetic co-crystals of anhydrous guanine and process for preparing the same GUR, Dvir (IL) 2024-01-02 US claimed
US-11415583-B2 Method, kit, and apparatus for cancer detection using urinary tumor markers NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2022-08-16 US claimed
US-20220098199-A1 SYNTHETIC CO-CRYSTALS OF ANHYDROUS GUANINE AND PROCESS FOR PREPARING THE SAME GUR, Dvir (IL) 2022-03-31 US claimed
US-20200150124-A1 METHOD, KIT, AND APPARATUS FOR CANCER DETECTION USING URINARY TUMOR MARKERS NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY 2020-05-14 US claimed
EP-3650862-A2 METHOD, KIT, AND APPARATUS FOR CANCER DETECTION USING URINARY TUMOR MARKERS National University Corporation Nagoya University (JP) 2020-05-13 EP claimed
CN-110787158-A Application of D609 in preparing medicine for preventing and treating retina injury diseases 中山大学中山眼科中心 2020-02-14 CN claimed
US-20190293653-A1 URINE METABOLITE MARKER FOR CHILDHOOD CANCER HITACHI, LTD. (JP) 2019-09-26 US claimed
WO-2019175332-A1 BH4 PATHWAY INHIBITION AND USE THEREOF FOR TREATING T-CELL MEDIATED AUTOIMMUNE DISEASES OR HYPERSENSITIVITY IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2019-09-19 WO claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
WO-2000023448-A1 NOVEL PTERIN ANTINEOPLASTIC AGENTS MOHENO PHILLIP B B (US) 2000-04-27 WO claimed
WO-2000021509-A2 METHODS OF TREATMENT IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2000-04-20 WO claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
US-5534514-A ANTITUMOR AGENTS OR FOR TREATMENT OF LEUKEMIA USING MIXTURES OF XANTHOPTERIN AND ISOXANTHOPTERIN SUSPENSION OF CARRIER SAN DIEGO STATE UNIVERSITY (US) 1996-07-09 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0170414-B1 PROCESS FOR TREATING METAL SURFACE Hitachi Chemical Co., Ltd. (JP) 1991-04-17 EP claimed
US-4643793-A WITH MIXTURE OF COPPER COMPOUND, COMPLEXING AGENT, REDUCING AGENT, AND PH ADJUSTER IN PRESENCE OF NITROGEN HETEROCYCLE COMPOUND HITACHI CHEMICAL COMPANY, LTD. (JP) 1987-02-17 US claimed
EP-0170414-A2 Process for treating metal surface Hitachi Chemical Co., Ltd. (JP) 1986-02-05 EP claimed