Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthopterin SCHEMBL906220 | 0.84 | PIK3CG (0.46) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 | |
| Xanthopterin SCHEMBL6475885 | 0.82 | PIK3CG (0.45) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 | |
| SCHEMBL6239850 | 0.81 | PIK3CG (0.41) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 | |
| SCHEMBL25899100 | 0.80 | HSD17B10 (0.39) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 | |
| SCHEMBL3692533 | 0.79 | ADORA2A (0.57) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 | |
| SCHEMBL16023555 | 0.78 | NOS1 (0.40) | PIK3CGCA1CA2NOS1DHFR | |
| SCHEMBL15075219 | 0.77 | NOS1 (0.45) | NOS1DHFR | |
| Pterin-6-Carboxylic Acid SCHEMBL13820952 | 0.77 | DHFR (0.45) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 | |
| Pterin-6-Carboxylic Acid SCHEMBL31438602 | 0.77 | DHFR (0.45) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 | |
| SCHEMBL23270838 | 0.77 | PIK3CG (0.38) | PIK3CGADORA2APIK3CAPIK3CBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272307-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022150721-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-07-14 | — | — | WO | disclosed |