Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17654321 | 0.89 | ALDH1A1 (0.50) | HRH3TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL15924404 | 0.89 | ALDH1A1 (0.50) | HRH3TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL9484258 | 0.87 | THRA (0.53) | L3MBTL1PTPN11THRATHRBPTPN1 | |
| SCHEMBL9484995 | 0.87 | THRA (0.53) | L3MBTL1PTPN11THRATHRBPTPN1 | |
| SCHEMBL9483389 | 0.87 | THRA (0.53) | L3MBTL1PTPN11THRATHRBPTPN1 | |
| SCHEMBL9484989 | 0.87 | THRA (0.53) | L3MBTL1PTPN11THRATHRBPTPN1 | |
| SCHEMBL9477667 | 0.87 | THRA (0.53) | L3MBTL1PTPN11THRATHRBPTPN1 | |
| SCHEMBL9152857 | 0.86 | RARB (0.53) | TSHRPTPN11THRATHRBPTPN1 | |
| SCHEMBL10339089 | 0.86 | RARB (0.53) | TSHRPTPN11THRATHRBPTPN1 | |
| SCHEMBL9484097 | 0.85 | THRA (0.52) | L3MBTL1PTPN11THRATHRBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637624-B1 | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5417885-A | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0637624-A1 | Antiferroelectric liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1995-02-08 | — | — | EP | disclosed |