Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063132 | 1.00 | KMT2A (0.52) | KMT2AKDM4EPOLBKCNH2L3MBTL1 | |
| SCHEMBL9062877 | 0.82 | MEN1 (0.46) | KMT2AKDM4EKCNH2ABCB1MEN1 | |
| SCHEMBL9062878 | 0.82 | MEN1 (0.46) | KMT2AKDM4EKCNH2ABCB1MEN1 | |
| SCHEMBL7114181 | 0.82 | ADRB3 (0.54) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL11357639 | 0.81 | ADRB2 (0.54) | KDM4EKCNH2ABCB1ADRB2ADRB1 | |
| SCHEMBL7332908 | 0.80 | KDM4E (0.73) | KMT2AKDM4EPOLBKCNH2MEN1 | |
| SCHEMBL7952028 | 0.80 | L3MBTL1 (0.46) | KMT2AKDM4EPOLBL3MBTL1ABCB1 | |
| SCHEMBL7952030 | 0.80 | L3MBTL1 (0.46) | KMT2AKDM4EPOLBL3MBTL1ABCB1 | |
| SCHEMBL11824244 | 0.80 | L3MBTL1 (0.62) | KMT2AL3MBTL1MEN1ADRB2ADRB1 | |
| SCHEMBL7336472 | 0.79 | KDM4E (0.79) | KMT2AKDM4EPOLBKCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711284-A1 | 2-BENZOHETEROCYCLYLOXY OR THIOPROPANOLAMINE DERIVATIVES WITH ADRENO RECEPTOR AGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004047-A1 | 2-BENZOHETEROCYCLYLOXY OR THIOPROPANOLAMINE DERIVATIVES WITH ADRENO RECEPTOR AGONIST ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |