Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952030 | 1.00 | L3MBTL1 (0.46) | L3MBTL1POLBABCB1TSHRALDH1A1 | |
| SCHEMBL7961071 | 0.82 | POLB (0.52) | POLBABCB1TSHRALDH1A1MAPT | |
| SCHEMBL7961075 | 0.82 | POLB (0.52) | POLBABCB1TSHRALDH1A1MAPT | |
| SCHEMBL9063124 | 0.80 | KMT2A (0.52) | L3MBTL1POLBABCB1ALDH1A1KDM4E | |
| SCHEMBL9063132 | 0.80 | KMT2A (0.52) | L3MBTL1POLBABCB1ALDH1A1KDM4E | |
| SCHEMBL7962426 | 0.79 | POLB (0.50) | POLBTSHRALDH1A1MAPTGAA | |
| SCHEMBL7962428 | 0.79 | POLB (0.50) | POLBTSHRALDH1A1MAPTGAA | |
| SCHEMBL7123752 | 0.79 | L3MBTL1 (0.41) | L3MBTL1ABCB1TSHRKMT2A | |
| SCHEMBL11080480 | 0.76 | POLB (0.50) | L3MBTL1POLBABCB1TSHRALDH1A1 | |
| SCHEMBL1137833 | 0.75 | HTR1A (0.53) | L3MBTL1POLBALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265581-B1 | REACTING SPECIFIED EPOXIDE AND AMINE, REACTING PRODUCT WITH ACID TO FORM ACID ADDITION SALT | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6093735-A | TREATMENT OF TYPE II DIABETES AND OBESITY | ELI LILLY AND COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| US-6075040-A | OBESITY AND DIABETES | ELI LILLY AND COMPANY (US) | 2000-06-13 | — | — | US | disclosed |
| US-6060492-A | SIDE EFFECT REDUCTION | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| US-5977154-A | OBESITY, DIABETES | ELI LILLY AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1997010825-A1 | SELECTIVE β3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-27 | — | — | WO | disclosed |
| EP-0764640-A1 | Selective beta3 adrenergic agonists | ELI LILLY AND COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |