Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668308 | 0.82 | MAPT (0.49) | APEX1FFAR1HSD17B10ALDH1A1KMT2A | |
| SCHEMBL21102147 | 0.82 | APEX1 (0.60) | APEX1FFAR1HSD17B10CXCL12ALDH1A1 | |
| SCHEMBL8870019 | 0.80 | HSD17B10 (0.73) | APEX1FFAR1HSD17B10CXCL12ALDH1A1 | |
| SCHEMBL11887852 | 0.79 | FFAR1 (0.75) | APEX1FFAR1HSD17B10CXCL12ALDH1A1 | |
| SCHEMBL2651634 | 0.79 | GABRA1 (0.42) | APEX1CYP1A2MAPK1TDP1TSHR | |
| SCHEMBL11530319 | 0.79 | MAPK1 (0.38) | APEX1CYP1A2MAPK1TDP1TSHR | |
| SCHEMBL27445248 | 0.78 | MAOA (0.46) | HSD17B10CTSBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10808121 | 0.77 | MAOA (0.48) | ALDH1A1MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL8937136 | 0.76 | MAPK1 (0.44) | CYP1A2MAPK1TDP1TSHRPOLB | |
| SCHEMBL31134964 | 0.76 | MAPK1 (0.44) | CYP1A2MAPK1TDP1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563136-A | ADMINISTERING FOR GASTROINTESTINAL OR NERVOUS SYSTEM DISORDERS CONNECTED WITH CHOLECYSTOKININ AND GASTRIN | RHONE-POULENC RORER S.A. (FR) | 1996-10-08 | — | — | US | disclosed |