Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063795 | 0.90 | ABCB1 (0.70) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| Meliternatin SCHEMBL9063713 | 0.86 | CYP1A2 (0.55) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9063848 | 0.84 | CYP1A1 (0.58) | CYP3A4ALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL30669273 | 0.84 | CYP1A1 (0.58) | CYP3A4ALDH1A1HSD17B10KDM4EMAPT | |
| Hexamethoxyflavone SCHEMBL30232628 | 0.83 | MEN1 (0.74) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| Hexamethoxyflavone SCHEMBL987569 | 0.83 | MEN1 (0.74) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL34467238 | 0.81 | MAPT (0.72) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL4277299 | 0.80 | ADORA3 (0.76) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL16894654 | 0.80 | ADORA3 (0.72) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL31287150 | 0.80 | ADORA3 (0.72) | CYP3A4MEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742012-A2 | Pharmaceutical composition containing substance inhibiting HSP47 production | Kureha Chemical Industry Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |