Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063296 | 0.86 | CYP3A4 (0.60) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| SCHEMBL30637383 | 0.86 | ADORA3 (0.52) | CYP3A4CYP2C9MAPTALDH1A1HSD17B10 | |
| SCHEMBL9063795 | 0.81 | ABCB1 (0.70) | CYP1A2CYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL17938762 | 0.80 | XDH (0.69) | MAPTHSD17B10MEN1KMT2APOLB | |
| SCHEMBL38664093 | 0.80 | XDH (0.69) | MAPTHSD17B10MEN1KMT2APOLB | |
| SCHEMBL1114843 | 0.78 | ABCG2 (0.62) | CYP1A2CYP1A1CYP1B1MAPTHSD17B10 | |
| SCHEMBL9063848 | 0.77 | CYP1A1 (0.58) | CYP1A2CYP1A1CYP1B1CYP3A4MAPT | |
| SCHEMBL30669273 | 0.77 | CYP1A1 (0.58) | CYP1A2CYP1A1CYP1B1CYP3A4MAPT | |
| Demethoxykanugin SCHEMBL13582763 | 0.77 | CYP3A4 (0.78) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| SCHEMBL15477918 | 0.76 | KDM4E (0.68) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742012-A2 | Pharmaceutical composition containing substance inhibiting HSP47 production | Kureha Chemical Industry Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |