Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | BCL9 | O00512 | 11/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 11/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669273 | 1.00 | CYP1A1 (0.58) | CYP1A1CYP1A2CYP1B1BCL9CTNNB1 | |
| SCHEMBL9063296 | 0.84 | CYP3A4 (0.60) | CYP1A1CYP1A2CYP1B1ABCB1ABCG2 | |
| SCHEMBL15477918 | 0.83 | KDM4E (0.68) | CYP1A1CYP1A2CYP1B1ABCB1ABCG2 | |
| SCHEMBL29691925 | 0.83 | KDM4E (0.68) | CYP1A1CYP1A2CYP1B1ABCB1ABCG2 | |
| SCHEMBL988273 | 0.83 | ABCB1 (0.78) | BCL9CTNNB1ABCB1ABCG2ALOX5 | |
| SCHEMBL9063795 | 0.81 | ABCB1 (0.70) | CYP1A2ABCB1ABCG2ALOX5MAPT | |
| SCHEMBL16894627 | 0.80 | ADORA3 (0.64) | BCL9CTNNB1ABCB1ABCG2ALOX5 | |
| SCHEMBL31065460 | 0.79 | ALDH1A1 (0.68) | BCL9CTNNB1ABCB1ABCG2ALOX5 | |
| Meliternatin SCHEMBL9063713 | 0.77 | CYP1A2 (0.55) | CYP1A1CYP1A2CYP1B1ABCB1ABCG2 | |
| SCHEMBL7655709 | 0.76 | CYP1A2 (0.64) | CYP1A1CYP1A2CYP1B1ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102875539-A | Method for preparing meliternin | NANJING ZELANG AGRI DEV CO LTD | 2013-01-16 | — | — | CN | claimed |
| CN-102875539-A | Method for preparing meliternin | NANJING ZELANG AGRI DEV CO LTD | 2013-01-16 | — | — | CN | disclosed |
| CN-102875539-A | Method for preparing meliternin | NANJING ZELANG AGRI DEV CO LTD | 2013-01-16 | — | — | CN | disclosed |
| CN-102875539-A | Method for preparing meliternin | NANJING ZELANG AGRI DEV CO LTD | 2013-01-16 | — | — | CN | disclosed |
| EP-0742012-A2 | Pharmaceutical composition containing substance inhibiting HSP47 production | Kureha Chemical Industry Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |