Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AGER | Q15109 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27579530 | 0.81 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL8107250 | 0.80 | MAPK1 (0.39) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL5805787 | 0.80 | MAPK1 (0.36) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL10891206 | 0.77 | G6PC1 (0.50) | G6PC1SLC6A2SLC6A4SLC6A3CHRM2 | |
| SCHEMBL4476467 | 0.77 | G6PC1 (0.54) | G6PC1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL8809383 | 0.75 | SLC6A2 (0.43) | G6PC1SLC6A2SLC6A4SLC6A3CHRM2 | |
| SCHEMBL28083577 | 0.73 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10MAPK1TSHR | |
| SCHEMBL19557303 | 0.73 | CHRM2 (0.71) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL11303340 | 0.72 | ALDH1A1 (0.44) | CHRM2CHRM3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL515999 | 0.71 | G6PC1 (0.54) | G6PC1SLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |