Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805787 | 0.83 | MAPK1 (0.36) | MAPK1CHRM2CHRM1HTR1AADRA2A | |
| SCHEMBL9063369 | 0.80 | G6PC1 (0.43) | MAPK1CHRM2CHRM1HTR1AADRA2A | |
| SCHEMBL27589428 | 0.77 | ESR2 (0.43) | — | |
| SCHEMBL28083577 | 0.77 | ALDH1A1 (0.38) | MAPK1SMN1; SMN2ALDH1A1MAPTTRPM8 | |
| SCHEMBL27839997 | 0.75 | MAPK1 (0.38) | MAPK1CHRM2CHRM1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27820597 | 0.74 | MAPK1 (0.38) | MAPK1CHRM2CHRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4474636 | 0.72 | ADH1C (0.41) | NPSR1L3MBTL1RAB9A | |
| SCHEMBL4484272 | 0.72 | ADH1C (0.41) | NPSR1L3MBTL1RAB9A | |
| SCHEMBL11691432 | 0.72 | L3MBTL1 (0.46) | CHRM2CHRM1HTR1AADRA2ADRD1 | |
| SCHEMBL10399936 | 0.71 | ALDH1A1 (0.47) | MAPK1CHRM2CHRM1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986555-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055478-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-12-10 | — | — | WO | disclosed |