⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2462221 | 0.87 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL1506053 | 0.75 | ALDH1A1 (0.48) | — | |
| SCHEMBL3613613 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL12490523 | 0.72 | — | — | |
| SCHEMBL6589055 | 0.72 | — | — | |
| SCHEMBL17382654 | 0.70 | — | — | |
| SCHEMBL729436 | 0.70 | — | — | |
| SCHEMBL37468 | 0.70 | — | — | |
| Allylthiourea SCHEMBL1194236 | 0.70 | — | — | |
| SCHEMBL13289626 | 0.69 | DDAH1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066009-A1 | Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools | CHEMGENES CORP (US) | 2018-03-08 | — | — | US | claimed |
| US-20140350234-A1 | Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools | CHEMGENES CORPORATION (US) | 2014-11-27 | — | — | US | claimed |
| US-20110040082-A1 | Modifications of antimetabolite gemcitabine for incorporation in CpG oligonucleotides | SRIVASTAVA SURESH C | 2011-02-17 | — | — | US | claimed |
| US-20050191660-A1 | Labelled oligonucleotides synthesized on solid-supports | APPLERA CORPORATION (US) | 2005-09-01 | — | — | US | claimed |
| US-20030191303-A1 | Labelled oligonucleotides synthesized on solid-supports | APPLERA CORPORATION | 2003-10-09 | — | — | US | claimed |
| EP-1155027-B1 | SYNTHESIS OF LABELLED OLIGONUCLEOTIDES ON SOLID-SUPPORTS | APPLERA CORP (US) | 2003-10-01 | — | — | EP | claimed |
| US-6525183-B2 | Solid-support, a cleavable linker, moiety with >/= three attachment sites, a label, a nucleophile and an acid cleavable protecting group reacted in a cyclical fashion with a phosphoramidate protected nucleoside | PE CORPORATION (NY) | 2003-02-25 | — | — | US | claimed |
| US-20020165389-A1 | Multiple-labelled oligonucleotides synthesized on solid-supports | PE CORPORATION (NY) (US) | 2002-11-07 | — | — | US | claimed |
| EP-1155027-A2 | SYNTHESIS OF LABELLED OLIGONUCLEOTIDES ON SOLID-SUPPORTS | PE Corporation (NY) (US) | 2001-11-21 | — | — | EP | claimed |
| US-6316610-B2 | Hybrid stabilization | PE CORPORATION (NY) | 2001-11-13 | — | — | US | claimed |
| US-20010014735-A1 | Labelled oligonucleotides synthesized on solid-supports | PE CORPORATION (NY) | 2001-08-16 | — | — | US | claimed |
| US-6255476-B1 | REACTING A LABELLED SOLID SUPPORT OF GIVEN FORMULA TO REMOVE AN ACID CLEAVABLE PROTECTING GROUP, ADDING A 5'-PHOSPHORAMIDITE, 3'-PROTECTED NUCLEOSIDE AND AN ACTIVATOR TO FROM A BOND | PE CORPORATION (NY) | 2001-07-03 | — | — | US | claimed |
| WO-2000050432-A2 | SYNTHESIS OF LABELLED OLIGONUCLEOTIDES ON SOLID-SUPPORTS | PE CORPORATION (NY) (US) | 2000-08-31 | — | — | WO | claimed |
| US-20240174710-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS | WAVE LIFE SCIENCES LTD. (SG) | 2024-05-30 | — | — | US | disclosed |
| CN-113785007-B | Recycling method | 沃纳艾根科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11873316-B2 | Compositions and methods for phosphoramidite and oligonucleotide synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-16 | — | — | US | disclosed |
| WO-1993012135-A1 | NUCLEASE STABLE AND BINDING COMPETENT OLIGOMERS AND METHODS FOR THEIR USE | GILEAD SCIENCES, INC. (US) | 1993-06-24 | — | — | WO | disclosed |
| WO-1993010820-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| WO-1993001204-A1 | METHOD AND COMPOUNDS FOR RNA SYNTHESIS | APPLIED BIOSYSTEMS, INC. (US) | 1993-01-21 | — | — | WO | disclosed |
| WO-1993001204-A1 | METHOD AND COMPOUNDS FOR RNA SYNTHESIS | APPLIED BIOSYSTEMS, INC. (US) | 1993-01-21 | — | — | WO | disclosed |