Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.60 |
| ▸ | FDPS | P14324 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.39 |
| ▸ | LAP3 | P28838 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL266936 | 1.00 | DNM1 (0.60) | DNM1FDPSCYP3A4L3MBTL1GGPS1 | |
| Phosphoric Acid SCHEMBL7172651 | 0.97 | DNM1 (0.57) | DNM1FDPSCYP3A4L3MBTL1GGPS1 | |
| Phosphoric Acid SCHEMBL7178325 | 0.97 | DNM1 (0.57) | DNM1FDPSCYP3A4L3MBTL1GGPS1 | |
| Methyl Phosphonate SCHEMBL7181529 | 0.95 | DNM1 (0.55) | DNM1FDPSCYP3A4L3MBTL1GGPS1 | |
| Phosphoric Acid SCHEMBL10532007 | 0.92 | DNM1 (0.75) | DNM1FDPSGGPS1LAP3CA2 | |
| Phosphoric Acid SCHEMBL6908898 | 0.92 | FDPS (0.56) | DNM1FDPSGGPS1LAP3 | |
| SCHEMBL5070634 | 0.92 | DNM1 (0.52) | DNM1FDPSCYP3A4L3MBTL1GGPS1 | |
| SCHEMBL7892230 | 0.92 | DNM1 (0.52) | DNM1FDPSCYP3A4L3MBTL1GGPS1 | |
| Phosphoric Acid SCHEMBL6909609 | 0.92 | FDPS (0.56) | DNM1FDPSGGPS1LAP3 | |
| Methyl Phosphonate SCHEMBL7180319 | 0.92 | DNM1 (0.52) | DNM1FDPSCYP3A4L3MBTL1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299421-B1 | Imide modified epoxy resins | DOW CHEMICAL CO (US) | 1996-03-13 | — | — | EP | disclosed |
| EP-0399351-A2 | Epoxy resin and water borne coatings therefrom | THE DOW CHEMICAL COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4946911-A | CONTAINING UNSATURATED IMIDE | THE DOW CHEMICAL COMPANY (US) | 1990-08-07 | — | — | US | disclosed |
| US-4847348-A | BINDERS, COATINGS | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0299421-A2 | Imide modified epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1989-01-18 | — | — | EP | disclosed |