Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2256256 | 0.79 | CYP2A6 (0.54) | PPARGPPARACYP1A2CYP2A6AGXT | |
| SCHEMBL25331886 | 0.78 | SLC6A4 (0.39) | PPARGPPARAKDM4ESLC6A4 | |
| SCHEMBL3468664 | 0.78 | SLC6A4 (0.39) | PPARGPPARAKDM4ESLC6A4 | |
| SCHEMBL5701222 | 0.78 | PPARG (0.51) | PPARGPPARACYP1A2CYP2A6AGXT | |
| SCHEMBL8543515 | 0.77 | PPARG (0.51) | PPARGPPARACYP1A2CYP2A6AGXT | |
| SCHEMBL8886597 | 0.75 | KDM4E (0.49) | PPARGPPARAKDM4ETDP1ALOX5 | |
| SCHEMBL9614092 | 0.75 | PPARG (0.53) | PPARGPPARACYP1A2CYP2A6RAB9A | |
| SCHEMBL26190199 | 0.75 | PPARG (0.49) | PPARGPPARACYP1A2CYP2A6AGXT | |
| SCHEMBL16893876 | 0.75 | PPARG (0.49) | PPARGPPARACYP1A2CYP2A6AGXT | |
| SCHEMBL9064518 | 0.74 | CYP1A2 (0.48) | PPARGPPARACYP1A2CYP2A6AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733364-A1 | MEDICINAL COMPOSITION FOR CIRCULATORY ORGAN | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |