SCHEMBL3468664

SCHEMBL3468664

[CH2]C(CC)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.39
LTA4H P09960 3/20 0.39
CA4 P22748 1/20 0.39
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
KCNA3 P22001 1/20 0.36
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
KDM4E B2RXH2 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25331886 1.00 SLC6A4 (0.39) SLC6A4LTA4HCA4MTNR1AMTNR1B
SCHEMBL7350372 0.83 SLC6A4 (0.41) SLC6A4LTA4HCA4MTNR1AMTNR1B
SCHEMBL8886735 0.80 ACHE (0.41) LMNATSHRALDH1A1MAPTPPARG
SCHEMBL4635829 0.79 LTA4H (0.44) SLC6A4LTA4HLMNAALDH1A1KCNA3
SCHEMBL8886871 0.78 LDHA (0.42) SLC6A4LMNAALDH1A1MAPTKDM4E
SCHEMBL8890078 0.78 ALDH1A1 (0.40) SLC6A4ALDH1A1MAPTPPARGPPARA
SCHEMBL8995789 0.78 PPARA (0.40) SLC6A4TSHRPPARGPPARA
SCHEMBL28052557 0.78 ANPEP (0.41) SLC6A4CA4MTNR1AMTNR1BLMNA
SCHEMBL9064396 0.78 PPARG (0.51) SLC6A4KDM4EPPARGPPARA
SCHEMBL7976811 0.78 LTA4H (0.44) SLC6A4LTA4HLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120196995-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2012-08-02 US claimed
US-4958024-A REACTION OF CARBAMATE SUBSTITUTED ACRYLIC ESTER, VASODILATORS, HYPOTENSIVE AGENTS BANYU PHARMACEUTICAL COMPANY, LTD. (JP) 1990-09-18 US claimed
US-4914227-A FOR VASODILATING AND HYPOTENSIVE AGENTS BANYU PHARMACEUTICAL COMPANY, LTD. (JP) 1990-04-03 US claimed
US-4739106-A VASODILATION, HYPOTENSIVE AGENTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1988-04-19 US claimed
EP-0101023-B1 PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-07-29 EP claimed
EP-0101023-A1 Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process BANYU PHARMACEUTICAL CO., LTD. (JP) 1984-02-22 EP claimed
JP-63304003-A None JP disclosed
WO-2024005209-A1 1,4-CINEOLE DERIVATIVE AND INTERMEDIATE THEREOF, HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT, METHOD FOR USING HERBICIDE, AND METHOD FOR PREPARING AGROCHEMICAL COMPOSITION 北興化学工業株式会社 2024-01-04 WO disclosed
CN-115044244-A Packaging ink composition with low curing shrinkage rate and preparation method thereof 西安思摩威新材料有限公司 2022-09-13 CN disclosed
CN-112601668-B Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2022-07-29 CN disclosed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN disclosed
CN-110300772-B Polyoxazolidinones and process for their preparation 巴斯夫欧洲公司 2022-04-26 CN disclosed
CN-114008102-A Water-emulsifiable isocyanates having improved properties 巴斯夫欧洲公司 2022-02-01 CN disclosed
EP-0155580-B1 MONOAZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1987-01-28 EP disclosed
EP-0155580-A1 Monoazo dyestuffs, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1985-09-25 EP disclosed
US-4514401-A CARDIOTONICS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-04-30 US disclosed
US-4487772-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO. LTD. (JP) 1984-12-11 US disclosed
US-4468402-A Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-08-28 US disclosed
US-4454130-A CARDIOTONIC, HYPOTENSIVE AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-06-12 US disclosed
EP-0101023-A1 Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process BANYU PHARMACEUTICAL CO., LTD. (JP) 1984-02-22 EP disclosed