Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674907 | 0.94 | LMNA (0.42) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL4972071 | 0.88 | LMNA (0.39) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL8674666 | 0.87 | LMNA (0.42) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL371433 | 0.83 | CA1 (0.47) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL23430759 | 0.78 | EIF4A3 (0.37) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL1245089 | 0.78 | LMNA (0.65) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL20642320 | 0.78 | EIF4A3 (0.37) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL21145864 | 0.78 | LMNA (0.48) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL12297358 | 0.78 | LMNA (0.59) | LMNACA1CA2TRPA1CHRM1 | |
| SCHEMBL13588022 | 0.78 | GABRA1 (0.34) | LMNACA1CA2TRPA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728632-A | ODORLESS | KOCH INDUSTRIES, INC. (US) | 1988-03-01 | — | — | US | claimed |
| US-4680056-A | Carbonless paper solvent utilizing triisopropyltoluene | KOCH INDUSTRIES, INC. (US) | 1987-07-14 | — | — | US | claimed |
| EP-0708074-A1 | Process for the preparation of pyromellitic anhydride | MITSUBISHI OIL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |