SCHEMBL4972071

SCHEMBL4972071

Cc1cc(C)c(C(C)C)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TRPA1 O75762 1/20 0.37
CHRM1 P11229 1/20 0.37
SLC6A2 P23975 1/20 0.37
ADRA1A P35348 1/20 0.37
HTR2B P41595 1/20 0.37
GAA P10253 2/20 0.37
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.35
GFER P55789 1/20 0.35
GABRA1 P14867 4/20 0.35
GABRB1 P18505 3/20 0.35
GABRB2 P47870 2/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
GPR55 Q9Y2T6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8674907 0.94 LMNA (0.42) LMNACA1CA2TRPA1CHRM1
SCHEMBL9064530 0.88 LMNA (0.39) LMNACA1CA2TRPA1CHRM1
SCHEMBL8674666 0.87 LMNA (0.42) LMNACA1CA2TRPA1CHRM1
SCHEMBL10436723 0.81 CYP3A4 (0.36) LMNACYP3A4TSHRMAPK1
SCHEMBL23625218 0.78 LMNA (0.34) LMNACA1CA2TRPA1CHRM1
SCHEMBL12297358 0.78 LMNA (0.59) LMNACA1CA2TRPA1CHRM1
SCHEMBL14924905 0.78 LMNA (0.41) LMNACA1CA2TRPA1CHRM1
SCHEMBL1487434 0.78 LMNA (0.59) LMNACA1CA2TRPA1CHRM1
SCHEMBL13588022 0.78 GABRA1 (0.34) LMNACA1CA2TRPA1CHRM1
SCHEMBL23430759 0.78 EIF4A3 (0.37) LMNACA1CA2TRPA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1115321-C Production method of pyromellitic acid PETROCHEMISTRY INST HEILONGJIA (CN) 2003-07-23 CN claimed
CN-1245793-A Production method of pyromellitic acid BRANCH OF PETROCHEMISTRY INST (CN) 2000-03-01 CN claimed
CN-1245171-A Process for preparing sym-phenyltetraformic dianhydride INST OF PETRO CHEMISTRY HEILON (CN) 2000-02-23 CN claimed
US-3992418-A Production of pyromellitic dianhydride UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-11-16 US claimed
CN-115253988-A Pyromellitic acid continuous anhydride forming device 江苏正丹化学工业股份有限公司 2022-11-01 CN disclosed
CN-111960939-B Preparation method for preparing pyromellitic acid based on catalytic oxidation-hydrolysis-fractional crystallization 连云港鹏辰特种新材料有限公司 2021-12-28 CN disclosed
CN-111960939-A Preparation method for preparing pyromellitic acid based on catalytic oxidation-hydrolysis-fractional crystallization 连云港鹏辰特种新材料有限公司 2020-11-20 CN disclosed
US-20170044112-A1 HYDROPHOBICALLY TAGGED JANUS KINASE INHIBITORS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2017-02-16 US disclosed
CN-102153457-B Method for preparing 2,3,5-trimethyl hydroquinone intermediate (2,3,5-trimethyl benzoquinone) by unsym-trimethyl benzene oxidation NANTONG BAISHENG CHEMICAL CO LTD 2013-03-06 CN disclosed
CN-102659522-A Simple preparation method of 2,3,5-trimethylhydroquinone and method for preventing 2,3,5-trimethylhydroquinone from being oxidized in production or storage process UNIV SHANDONG 2012-09-12 CN disclosed
CN-102153457-A Method for preparing 2,3,5-trimethyl hydroquinone intermediate (2,3,5-trimethyl benzoquinone) by unsym-trimethyl benzene oxidation NANTONG BAISHENG CHEMICAL CO LTD 2011-08-17 CN disclosed
CN-101033174-B Method for preparing 2,3,5-trimethylphenol ANHUI KELIAN IND CO LTD 2010-11-24 CN disclosed
CN-1245171-A Process for preparing sym-phenyltetraformic dianhydride INST OF PETRO CHEMISTRY HEILON (CN) 2000-02-23 CN disclosed
CN-1136041-A Rifinement of pyromellitic acid dianhydride by hot air carrying process WEN DIANWU (CN) 1996-11-20 CN disclosed
EP-0629680-A1 Process for separating high purity durene UOP (US) 1994-12-21 EP disclosed
US-5223589-A Lithium-exchaged X zeolite as adsorbent UOP (US) 1993-06-29 US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
US-4014755-A Method of refining pyromellitic acid dianhydride VEBA-CHEMIE AG (DT) 1977-03-29 US disclosed
US-3992418-A Production of pyromellitic dianhydride UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-11-16 US disclosed
US-3992418-A Production of pyromellitic dianhydride UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044112-A1 HYDROPHOBICALLY TAGGED JANUS KINASE INHIBITORS AND USES THEREOF JAK1, JAK3, JAK2 LMNA 4834/4885CA1 4198/4885CA2 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.