SCHEMBL9064658

SCHEMBL9064658

CC1CN(c2cccc(C(F)(F)F)c2)C(=NC(=O)C(F)(F)F)S1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.42
ACACB O00763 2/20 0.40
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 4/20 0.38
KMT2A Q03164 1/20 0.37
LMNA P02545 2/20 0.37
HTT P42858 2/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428115 0.92 NOTUM (0.41) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL9064539 0.90 NOTUM (0.43) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL8425728 0.87 NOTUM (0.41) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL8427989 0.87 NOTUM (0.41) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL9064745 0.87 ACACB (0.41) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL8424243 0.87 NOTUM (0.41) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL9064664 0.86 LMNA (0.43) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL8425429 0.86 ACACB (0.41) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL8428411 0.85 NOTUM (0.39) NOTUMACACBMAPK1HSD17B10POLB
SCHEMBL9064735 0.84 ALDH1A1 (0.45) NOTUMMAPK1HSD17B10POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5070308-A None JP disclosed
JP-5070312-A None JP disclosed
US-5508415-A HAVING STRONG HERBICIDAL POTENCY, NOTICEABLE SELECTIVITY BETWEEN CROP PLANTS AND WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-16 US disclosed
US-5426188-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-20 US disclosed
US-5360912-A Cyclization of thiourea derivatives by acid treatment SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-01 US disclosed
US-5292715-A Iminothiazolines, their production and use as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-08 US disclosed
US-5244863-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-09-14 US disclosed
EP-0545431-A1 Process of producing iminothiyzoline derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-06-09 EP disclosed
JP-H0570308-A HERBICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1993-03-23 JP disclosed
JP-H0570312-A HERBICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1993-03-23 JP disclosed
EP-0529481-A1 Iminothiazolines, their production and use as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-03 EP disclosed
JP-H00570312-A 0001-01-01 JP disclosed
JP-H00570308-A 0001-01-01 JP disclosed