SCHEMBL9064745

SCHEMBL9064745

COC(=O)N=C1SC(C)CN1c1cccc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.41
NOTUM Q6P988 1/20 0.41
POLB P06746 2/20 0.40
HSD17B10 Q99714 4/20 0.39
LMNA P02545 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39
TSHR P16473 4/20 0.39
TP53 P04637 2/20 0.39
USP2 O75604 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPT P10636 2/20 0.39
NPC1 O15118 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064735 0.89 ALDH1A1 (0.45) NOTUMPOLBHSD17B10LMNASMN1; SMN2
SCHEMBL9450012 0.88 ACACB (0.41) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL9064539 0.88 NOTUM (0.43) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL9064658 0.87 NOTUM (0.42) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL9428115 0.86 NOTUM (0.41) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL8424243 0.85 NOTUM (0.41) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL8425728 0.85 NOTUM (0.41) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL8427989 0.85 NOTUM (0.41) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL9064664 0.84 LMNA (0.43) ACACBNOTUMPOLBHSD17B10LMNA
SCHEMBL8425429 0.84 ACACB (0.41) ACACBNOTUMPOLBHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508415-A HAVING STRONG HERBICIDAL POTENCY, NOTICEABLE SELECTIVITY BETWEEN CROP PLANTS AND WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-16 US disclosed
US-5426188-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-20 US disclosed
EP-0446802-B1 Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 1995-06-07 EP disclosed
US-5244863-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-09-14 US disclosed