SCHEMBL9064744

SCHEMBL9064744

CC1=CC(=O)N(c2ccccc2C(C)C)C1=O

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.62
FAAH O00519 1/20 0.62
DPP4 P27487 3/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
ALOX15 P16050 1/20 0.38
HCAR1 Q9BXC0 1/20 0.38
ANPEP P15144 3/20 0.37
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TLR9 Q9NR96 1/20 0.34
RGS12 O14924 1/20 0.33
PKM P14618 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7193393 0.84 TLR9 (0.48) MGLLFAAHNR1H2NR1H3MAPT
SCHEMBL9492119 0.79 MGLL (0.60) MGLLNR1H2NR1H3ALOX15MAPT
SCHEMBL30473083 0.79 MGLL (0.60) MGLLNR1H2NR1H3ALOX15MAPT
SCHEMBL2229804 0.77 TLR9 (0.63) MGLLFAAHMAPTALDH1A1TLR9
SCHEMBL9200421 0.77 MGLL (0.37) MGLLFAAHMAPTRGS12PKM
SCHEMBL9200403 0.77 MGLL (0.37) MGLLFAAHMAPTALDH1A1RGS12
SCHEMBL9200416 0.77 MGLL (0.37) MGLLFAAHMAPTALDH1A1RGS12
SCHEMBL29707903 0.77 MGLL (1.00) MGLLFAAHDPP4NR1H2NR1H3
SCHEMBL3482778 0.77 MGLL (1.00) MGLLFAAHDPP4NR1H2NR1H3
SCHEMBL3679861 0.77 MGLL (0.38) MGLLFAAHMAPTALDH1A1TLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523360-A IMPROVES MELT-FLOW PROPERTIES AKZO NOBEL N. V. (NL) 1996-06-04 US disclosed
EP-0495545-B1 Citraconimide (co)polymers and curing with anionic catalyst AKZO NOBEL NV (NL) 1994-12-28 EP disclosed
US-5221717-A CITRACONIMIDE (CO)POLYMERS AND CURING WITH ANIONIC CATALYST AKZO N.V. (NL) 1993-06-22 US disclosed
EP-0495545-A1 Citraconimide (co)polymers and curing with anionic catalyst Akzo Nobel N.V. (NL) 1992-07-22 EP disclosed