SCHEMBL3482778

SCHEMBL3482778

CC(C)c1ccccc1N1C(=O)C=CC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 1.00
FAAH O00519 1/20 1.00
TLR9 Q9NR96 2/20 0.61
ALDH1A1 P00352 2/20 0.43
HSP90AA1 P07900 2/20 0.43
PKM P14618 1/20 0.43
CCR6 P51684 1/20 0.43
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALOX15 P16050 1/20 0.42
HCAR1 Q9BXC0 1/20 0.42
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
DPP4 P27487 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29707903 1.00 MGLL (1.00) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL3875399 0.82 MGLL (0.69) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL28411421 0.79 MGLL (0.66) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL29377102 0.78 TLR9 (1.00) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL121404 0.78 TLR9 (1.00) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL2032898 0.78 MGLL (0.63) MGLLFAAHTLR9HSP90AA1DPP4
SCHEMBL9064744 0.77 MGLL (0.62) MGLLFAAHTLR9ALDH1A1PKM
SCHEMBL23430011 0.77 MGLL (0.61) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL20097784 0.76 FAAH (0.61) MGLLFAAHALDH1A1ALOX15HCAR1
SCHEMBL9084081 0.74 TLR9 (0.73) MGLLFAAHTLR9ALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
US-5618844-A MATRIX METALLOPROTEINASE INHIBITOR SANOFI S.A. (FR) 1997-04-08 US claimed
US-20250092171-A1 HIGH-PURITY 4-(2-BROMOETHYL)BENZENESULFONIC ACID, HIGH-PURITY STYRENESULFONIC ACID COMPOUND DERIVED THEREFROM, AND POLYMER THEREOF, AND METHODS FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2025-03-20 US disclosed
EP-3666753-B1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORP (JP) 2024-09-11 EP disclosed
US-20240191087-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS INC (US) 2024-06-13 US disclosed
CN-118151284-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151280-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151283-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151281-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151285-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151282-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
US-20040063887-A1 Transparent heat-resistant resin optical material and film TOSOH CORPORATION (JP) 2004-04-01 US disclosed
EP-1403297-A1 Transparent heat-resistant resin optical material and film Tosoh Corporation (JP) 2004-03-31 EP disclosed
EP-0723980-B1 Thermoplastic moulding materials with improved thermostability BAYER AG (DE) 1998-09-02 EP disclosed
US-5726265-A N-(2-ETHYL-6-METHYL)PHENYLMALEIMIDE-ACRYLONITRILE-STYRENE TERPOLYMER BAYER AKTIENGESELLSCHAFT (DE) 1998-03-10 US disclosed
US-5714541-A A MOLDING MATERIALS BLEND COMPRISING A GRAFT RUBBER AND A COPOLYMER FORMED FROM N-(2-ETHYL-6-METHYL)PHENYLMALEIMIDE WITH TWO OR MORE MONOMERS, I.E., STYRENE, ACRYLONITRILE, METHYL METHACRYLATE, ALPHA-METHYLSTYRENE; NONDISCOLORING BAYER AKTIENGESELLSCHAFT (DE) 1998-02-03 US disclosed
US-5684163-A Process for the preparation of N-(ortho-alkylphenyl)-imides BAYER AKTIENGESELLSCHAFT (DE) 1997-11-04 US disclosed
US-5618844-A MATRIX METALLOPROTEINASE INHIBITOR SANOFI S.A. (FR) 1997-04-08 US disclosed
EP-0726253-A1 Process for the preparation of N-(ortho-alkyl-phenyl)-imides BAYER AG (DE) 1996-08-14 EP disclosed
EP-0723980-A1 Thermoplastic moulding materials with improved thermostability BAYER AG (DE) 1996-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092171-A1 HIGH-PURITY 4-(2-BROMOETHYL)BENZENESULFONIC ACID, HIGH-PURITY STYRENESULFONIC ACID COMPOUND DERIVED THEREFROM, AND POLYMER THEREOF, AND METHODS FOR PRODUCING SAME BRPF1, WEE2, WEE1 MGLL 4545/4885FAAH 4723/4885TLR9 3553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.