Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.53 |
| ▸ | CES1 | P23141 | 8/20 | 0.53 |
| ▸ | CES2 | O00748 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28207296 | 1.00 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL2573096 | 0.92 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL638951 | 0.92 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| Bromide SCHEMBL6552300 | 0.90 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL196410 | 0.90 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Bromide SCHEMBL1244460 | 0.90 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Fluoride SCHEMBL10493503 | 0.90 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Water SCHEMBL11595702 | 0.90 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Water SCHEMBL3120172 | 0.90 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Iodide SCHEMBL8433341 | 0.90 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851567-A | Pyrazine compounds and its application | 中国科学院上海有机化学研究所 | 2019-06-07 | — | — | CN | claimed |
| CN-109504015-A | Electrochromic polymeric compounds material based on combined strategy and prepare electrochromic device | 常州铱视光电科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109055743-A | A kind of extracts composition and its application | 中国科学院上海有机化学研究所 | 2018-12-21 | — | — | CN | claimed |
| CN-108950247-A | A kind of extraction system and its application | 中国科学院上海有机化学研究所 | 2018-12-07 | — | — | CN | claimed |
| CN-108754141-A | A kind of extraction organic phase and its application | 中国科学院上海有机化学研究所 | 2018-11-06 | — | — | CN | claimed |
| CN-108103317-A | A kind of method that lithium is recycled from waste liquid containing lithium | 中国科学院上海有机化学研究所 | 2018-06-01 | — | — | CN | claimed |
| CN-107068288-A | The wrapped submarine communication composite cable of polyvinyl chloride/polyacrylic acid waterstop | 芜湖航天特种电缆厂股份有限公司 | 2017-08-18 | — | — | CN | claimed |
| CN-106782863-A | The wrapped submarine communication composite cable of polyvinyl chloride/polyamide waterstop | 芜湖航天特种电缆厂股份有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106710676-A | Submarine communication composite cable with modified polyvinyl chloride sheath | 芜湖航天特种电缆厂股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-106710673-A | Submarine communication composite cable equipped with modified polyethylene sheath | 芜湖航天特种电缆厂股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-106710675-A | Polyvinyl chloride/polyvinyl alcohol water-blocking tape wrapped undersea communication integrated cable | 芜湖航天特种电缆厂股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-106710674-A | Submarine communication comprehensive cable coated with polyvinyl chloride/polyethylene oxide water-blocking tape | 芜湖航天特种电缆厂股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-106653182-A | Seabed communication composite cable with modified polyacrylonitrile sheath | 芜湖航天特种电缆厂股份有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106653181-A | Seabed communication comprehensive cable with modified polypropylene sheath | 芜湖航天特种电缆厂股份有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106531346-A | Submarine communication integral cable wrapped by polyvinyl chloride/polyisobutene water blocking tape | 芜湖航天特种电缆厂股份有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-104402909-B | A kind of synthetic method of cefoxitin acid | 盐城开元医药化工有限公司 | 2017-03-15 | — | — | CN | claimed |
| CN-105838350-A | Electrochromic composite material and prepared electrochromic device | 吉林大学 | 2016-08-10 | — | — | CN | claimed |
| CN-107074794-B | Method for producing polyvalent glycidyl compound | 昭和电工株式会社 | 2019-09-24 | — | — | CN | disclosed |
| EP-0548560-A2 | Process for the manufacturing of halomaleic and halofumaric esters | AMERICAN CYANAMID COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5214198-A | Dehydrohalogenation, phase tranfer catalyst | AMERICAN CYANAMID COMPANY (US) | 1993-05-25 | — | — | US | disclosed |