Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Calcium Hypochloride SCHEMBL20269 | 1.00 | — | — | |
| Water SCHEMBL11617084 | 0.89 | — | — | |
| Water SCHEMBL966054 | 0.89 | — | — | |
| Water SCHEMBL1678934 | 0.89 | — | — | |
| Lithium Ion SCHEMBL11211373 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL820062 | 0.89 | — | — | |
| SCHEMBL4551808 | 0.89 | — | — | |
| SCHEMBL3802559 | 0.89 | — | — | |
| SCHEMBL1685170 | 0.89 | — | — | |
| Water SCHEMBL632408 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571535-A | Treatment of topical infections | FLOWERS MARIANNE (US) | 1996-11-05 | — | — | US | claimed |
| EP-0559791-A4 | TREATMENT OF TOPICAL INFECTIONS | — | 1993-10-20 | — | — | EP | claimed |
| EP-0559791-A1 | TREATMENT OF TOPICAL INFECTIONS | FLOWERS, Marianne (US) | 1993-09-15 | — | — | EP | claimed |
| WO-1992009291-A1 | TREATMENT OF TOPICAL INFECTIONS | FLOWERS MARIANNE (US) | 1992-06-11 | — | — | WO | claimed |
| US-5571535-A | Treatment of topical infections | FLOWERS MARIANNE (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0559791-A4 | TREATMENT OF TOPICAL INFECTIONS | — | 1993-10-20 | — | — | EP | disclosed |
| EP-0559791-A1 | TREATMENT OF TOPICAL INFECTIONS | FLOWERS, Marianne (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009291-A1 | TREATMENT OF TOPICAL INFECTIONS | FLOWERS MARIANNE (US) | 1992-06-11 | — | — | WO | disclosed |