Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244302 | 0.74 | CHRNB2 (0.46) | CHRNB2CHRNA4DRD2DRD3SLC6A2 | |
| SCHEMBL10262733 | 0.71 | CHRNB2 (0.44) | CHRNB2CHRNA4DRD2DRD3SLC6A2 | |
| SCHEMBL2047177 | 0.71 | CHRNB2 (0.47) | CHRNB2CHRNA4DRD2DRD3 | |
| SCHEMBL4250760 | 0.69 | ALDH1A1 (0.45) | CHRNB2CHRNA4DRD2DRD3SLC6A2 | |
| SCHEMBL2050822 | 0.69 | ESR1 (0.44) | CHRNB2CHRNA4DRD2DRD3ESR1 | |
| SCHEMBL4268386 | 0.66 | CHRNB2 (0.40) | CHRNB2CHRNA4DRD2DRD3SLC6A2 | |
| SCHEMBL24650841 | 0.65 | DPP4 (0.40) | CHRNB2CHRNA4DRD2DRD3SLC6A2 | |
| SCHEMBL9534010 | 0.64 | ESR1 (0.51) | DRD2DRD3ESR1ESR2CYP1A1 | |
| SCHEMBL13518633 | 0.64 | ESR1 (0.51) | DRD2DRD3ESR1ESR2CYP1A1 | |
| SCHEMBL10955529 | 0.63 | ADRA2A (0.39) | CHRNB2CHRNA4DRD2BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747406-A1 | Process for producing syndiotactic/isotactic block polyolefins | FINA TECHNOLOGY, INC. (US) | 1996-12-11 | — | — | EP | claimed |