SCHEMBL9065006

SCHEMBL9065006

CCOc1ccc(-c2cccc(C)c2-c2ccc(OCC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
TP53 P04637 3/20 0.50
GAA P10253 1/20 0.50
MAPK1 P28482 1/20 0.50
NQO1 P15559 1/20 0.48
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.46
LTA4H P09960 1/20 0.43
HPGD P15428 2/20 0.42
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
SRC P12931 1/20 0.41
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14539085 0.84 NPC1 (0.61) SMN1; SMN2NPC1RAB9ATP53GAA
SCHEMBL6013603 0.79 NQO1 (0.64) SMN1; SMN2NPC1RAB9ATP53GAA
SCHEMBL4928604 0.76 MAPT (0.50) SMN1; SMN2NPC1RAB9ATP53GAA
SCHEMBL5698011 0.76 LTA4H (0.61) SMN1; SMN2NPC1RAB9ATP53GAA
SCHEMBL3355657 0.75 ENPP1 (0.42) NPC1RAB9ATDP1
SCHEMBL396847 0.75 TDP1 (0.53) SMN1; SMN2NPC1RAB9ATP53GAA
SCHEMBL15224619 0.75 USP8 (0.35) SMN1; SMN2HPGDALDH1A1
SCHEMBL13211652 0.74 NQO1 (0.56) SMN1; SMN2NPC1RAB9ATP53GAA
SCHEMBL2163513 0.74 CYP3A4 (0.42) TP53TDP1MAPTALDH1A1CYP3A4
Methane SCHEMBL11860700 0.74 ENPP1 (0.41) NPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281162-B1 Method for improving the electrical insulating characteristics of a fraction, electrical insulating substance, and electrical appliances containing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-06-12 EP disclosed
EP-0115065-B1 PROCESS FOR PREPARING OIL-CONTAINING ELECTRICAL APPLIANCES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-09-06 EP disclosed
EP-0281162-A2 Method for improving the electrical insulating characteristics of a fraction, electrical insulating substance, and electrical appliances containing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-07 EP disclosed
US-4681980-A AROMATIC OLEFIN OIL NIPPON PETROCHEMICALS COMPANY LIMITED (JP) 1987-07-21 US disclosed
EP-0115065-A2 Process for preparing oil-containing electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-08-08 EP disclosed