Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396847 | 0.86 | TDP1 (0.53) | MAPTTDP1TSHRNQO1TP53 | |
| SCHEMBL3491387 | 0.80 | ABL1 (0.52) | MAPTTDP1TSHRTP53CYP3A4 | |
| SCHEMBL28508524 | 0.80 | KEAP1 (0.54) | KDM4ESMN1; SMN2ALDH1A1LTA4H | |
| SCHEMBL6013603 | 0.79 | NQO1 (0.64) | MAPTTDP1TSHRNQO1TP53 | |
| SCHEMBL5838057 | 0.77 | MAPT (0.50) | MAPTTDP1TSHRNQO1SMN1; SMN2 | |
| SCHEMBL9065006 | 0.76 | SMN1; SMN2 (0.50) | MAPTTDP1TSHRNQO1TP53 | |
| Propane SCHEMBL10492409 | 0.76 | ALDH1A1 (0.58) | MAPTTSHRCYP3A4KDM4ENPC1 | |
| Propane SCHEMBL9646509 | 0.76 | ALDH1A1 (0.58) | MAPTTSHRCYP3A4KDM4ENPC1 | |
| SCHEMBL5698011 | 0.76 | LTA4H (0.61) | MAPTTDP1TSHRNQO1TP53 | |
| SCHEMBL4583516 | 0.74 | CHRNB4 (0.46) | MAPTTDP1TSHRNQO1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021069-A1 | Receptor Function Regulating Agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021069-A1 | Receptor Function Regulating Agent | GPR119, INSR, GPR65 | MAPT 4574/4885TDP1 4558/4885TSHR 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.