Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28938777 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HCAR2PAMATMNAAA | |
| SCHEMBL9065697 | 0.82 | MEN1 (0.32) | MEN1KMT2ATSHR | |
| SCHEMBL30902654 | 0.81 | NAAA (0.44) | ALDH1A1HCAR2ATMMEN1KMT2A | |
| SCHEMBL31462326 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HCAR2ATMNAAAL3MBTL1 | |
| SCHEMBL28518298 | 0.79 | MEN1 (0.44) | ALDH1A1PAMATMMEN1KMT2A | |
| SCHEMBL2276500 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HCAR2ATMMEN1KMT2A | |
| SCHEMBL6063279 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HCAR2PAMATMMEN1 | |
| SCHEMBL9000912 | 0.77 | MEN1 (0.53) | ALDH1A1PAMATMMEN1KMT2A | |
| SCHEMBL28314622 | 0.77 | NAAA (0.44) | ALDH1A1HCAR2ATMMEN1KMT2A | |
| SCHEMBL5796303 | 0.76 | CYP4F2 (0.45) | ALDH1A1PAMATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | claimed |
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |