Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452622 | 0.83 | HCAR2 (0.41) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL9065007 | 0.82 | ALDH1A1 (0.34) | MEN1KMT2ATSHR | |
| SCHEMBL30440649 | 0.81 | MEN1 (0.47) | MEN1KMT2ATSHR | |
| SCHEMBL9065849 | 0.80 | CHRM2 (0.34) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL455718 | 0.80 | ALDH1A1 (0.48) | TSHR | |
| SCHEMBL9065316 | 0.80 | MEN1 (0.32) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL1748129 | 0.80 | TSHR (0.36) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL456197 | 0.79 | MEN1 (0.48) | MEN1KMT2ATSHR | |
| SCHEMBL11034348 | 0.78 | NAAA (0.47) | TSHR | |
| SCHEMBL6423478 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |