Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393718 | 0.94 | TSHR (0.40) | LMNAACHEALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3911811 | 0.89 | ACHE (0.47) | LMNAACHEHPGDGAABCHE | |
| SCHEMBL10394075 | 0.84 | ALDH1A1 (0.39) | LMNAACHEALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3909908 | 0.82 | ACHE (0.44) | ACHEALDH1A1HPGDMAPTNPEPPS | |
| SCHEMBL9327996 | 0.76 | LMNA (0.53) | LMNAACHEALDH1A1HPGDGAA | |
| SCHEMBL3905199 | 0.76 | SLC6A2 (0.41) | LMNAACHEHPGDSMN1; SMN2MAPT | |
| SCHEMBL3900452 | 0.71 | ACHE (0.45) | LMNAACHEALDH1A1HPGDGAA | |
| SCHEMBL3895790 | 0.70 | ACHE (0.43) | ACHEHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3899768 | 0.70 | ACHE (0.43) | ACHEALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL28825748 | 0.69 | HPGD (0.41) | LMNAACHEALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536083-B1 | Process for the synthesis of dialkyl succinylsuccinate esters and their conversion to dialkyl 2,5-diarylamino-3,6-dihydroterephthalate esters | CIBA GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| EP-0536083-A1 | Process for the synthesis of dialkyl succinylsuccinate esters and their conversion to dialkyl 2,5-diarylamino-3,6-dihydroterephthalate esters | CIBA-GEIGY AG (CH) | 1993-04-07 | — | — | EP | disclosed |
| US-4956464-A | Cyclization, dehydrogenation in the vapor phase or solid phase in the presence of an oxidizer | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |