Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384629 | 0.98 | KDM4E (0.47) | KDM4EKMT2ALMNACA12USP2 | |
| SCHEMBL9065124 | 0.96 | KDM4E (0.46) | KDM4EKMT2ALMNACA12USP2 | |
| SCHEMBL12322592 | 0.73 | FABP6 (0.47) | KDM4ECA12CA1CA2CA4 | |
| SCHEMBL12261833 | 0.73 | MAOA (0.35) | KDM4EKMT2ALMNACA12USP2 | |
| SCHEMBL434876 | 0.71 | MEN1 (0.41) | KMT2ACA12CA1CA2CA4 | |
| SCHEMBL25802522 | 0.69 | CA9 (0.38) | KDM4EKMT2ALMNACA12USP2 | |
| SCHEMBL3380497 | 0.68 | HSP90AA1 (0.40) | KDM4EKMT2ALMNACA12USP2 | |
| SCHEMBL10335124 | 0.67 | PKM (0.39) | KDM4EKMT2ALMNACA12USP2 | |
| SCHEMBL9016896 | 0.65 | GPR3 (0.50) | KDM4EKMT2ALMNACA12USP2 | |
| Saccharin SCHEMBL19212508 | 0.65 | CA12 (0.96) | KDM4EKMT2ALMNACA12USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525729-A | FLUORINATING CARBANIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |