Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15995171 | 0.91 | LMNA (0.42) | CES1TDP1CYP3A4MAPTMAPK1 | |
| SCHEMBL15189643 | 0.80 | ESR1 (0.46) | TDP1CYP3A4MAPTMAPK1KDM4E | |
| SCHEMBL10524449 | 0.80 | CES2 (0.50) | CES1CYP3A4MAPTMAPK1KDM4E | |
| SCHEMBL15564539 | 0.79 | OPRM1 (0.50) | CES1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL26987819 | 0.78 | MAPT (0.50) | CES1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL13562901 | 0.76 | LMNA (0.52) | CES1TDP1CYP3A4MAPTMAPK1 | |
| SCHEMBL11341980 | 0.74 | CES1 (0.46) | CES1TDP1CYP3A4MAPTMAPK1 | |
| SCHEMBL6698945 | 0.74 | CES1 (0.46) | CES1TDP1CYP3A4MAPTMAPK1 | |
| SCHEMBL29767713 | 0.73 | TDP1 (0.46) | CES1TDP1CYP3A4MAPTMAPK1 | |
| SCHEMBL8396816 | 0.73 | LMNA (0.44) | CES1TDP1CYP3A4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533013-B1 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1995-10-18 | — | — | EP | claimed |
| EP-0533013-A2 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1993-03-24 | — | — | EP | claimed |
| JP-5246943-A | — | — | None | — | — | JP | disclosed |
| CN-108530400-A | 1- deoxidation bearing taxanes of C-2 and C-4 modifications and preparation method thereof | 上海大学 | 2018-09-14 | — | — | CN | disclosed |
| US-5498750-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| US-5498750-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0533013-B1 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| US-5434303-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-18 | — | — | US | disclosed |
| US-5434303-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-18 | — | — | US | disclosed |
| JP-H05246943-A | METHOD FOR PREPARATION OF 1-FLUORO-CYCLOPROPANE-1-CARBOXYLIC ACID | BAYER AG | 1993-09-24 | — | — | JP | disclosed |
| EP-0533013-A3 | PROCESS FOR THE PRODUCTION OF 1-FLUOR-CYCLOPROPANE-1-CARBOXYLIC ACID | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0533013-A2 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| EP-0533013-A2 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |