Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180783 | 0.90 | MGAM (0.36) | TSHR | |
| SCHEMBL7642552 | 0.77 | LDHA (0.36) | — | |
| SCHEMBL11428981 | 0.74 | — | — | |
| SCHEMBL7166540 | 0.70 | TSHR (0.40) | ALOX15HSD17B10TSHR | |
| SCHEMBL9065165 | 0.70 | TSHR (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL9065268 | 0.69 | PRKCA (0.32) | TSHR | |
| SCHEMBL1007583 | 0.69 | TSHR (0.45) | HSD17B10TSHRCYP2D6CYP2C19 | |
| SCHEMBL527804 | 0.69 | TSHR (0.47) | ALOX15HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL7761810 | 0.68 | TSHR (0.50) | ALOX15HSD17B10TSHR | |
| SCHEMBL876025 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |