Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17213197 | 0.82 | CYP19A1 (0.49) | CYP19A1CYP17A1SCN1ASCN2ASCN3A | |
| SCHEMBL4597731 | 0.82 | CYP19A1 (0.49) | CYP19A1CYP17A1SCN1ASCN2ASCN3A | |
| SCHEMBL5978171 | 0.77 | NAAA (0.37) | CYP19A1CYP17A1 | |
| SCHEMBL17213209 | 0.77 | CYP19A1 (0.49) | CYP19A1CYP17A1SCN1ASCN2ASCN3A | |
| SCHEMBL4598002 | 0.77 | CYP19A1 (0.49) | CYP19A1CYP17A1SCN1ASCN2ASCN3A | |
| Acrylic Acid SCHEMBL28320730 | 0.73 | THRB (0.36) | CYP19A1CYP17A1 | |
| Acrylic Acid Methyl Ester SCHEMBL28271141 | 0.73 | ALDH1A1 (0.34) | CYP19A1 | |
| SCHEMBL45476 | 0.73 | NAAA (0.40) | CYP19A1CYP17A1SCN1ASCN2ASCN3A | |
| SCHEMBL28131970 | 0.72 | CYP2C19 (0.44) | — | |
| SCHEMBL28138951 | 0.71 | NAAA (0.39) | CYP19A1CYP17A1SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534605-A | Hydrophilic oxygen permeable polymers | BAUSCH & LOMB INCORPORATED (US) | 1996-07-09 | — | — | US | disclosed |
| US-5357013-A | (meth) acrylated polysiloxanes copolymerized with vinyl containing oxazolinone wetting agents | BAUSCH & LOMB INCORPORATED (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0338656-B1 | Polymeric silicone-based materials with high oxygen permeability | BAUSCH & LOMB (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0328340-B1 | HYDROPHILIC OXYGEN PERMEABLE POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 1993-03-31 | — | — | EP | disclosed |
| US-4910277-A | Blend of polysiloxane and an interior wetting agent | BAUSCH & LOMB INCORPORATED | 1990-03-20 | — | — | US | disclosed |
| EP-0338656-A2 | Polymeric silicone-based materials with high oxygen permeability | BAUSCH & LOMB INCORPORATED (US) | 1989-10-25 | — | — | EP | disclosed |
| EP-0328340-A2 | Hydrophilic oxygen permeable polymers | BAUSCH & LOMB INCORPORATED (US) | 1989-08-16 | — | — | EP | disclosed |
| US-4810764-A | CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |