Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802304 | 0.83 | ALDH1A1 (0.48) | RAB9ANPC1HPGDTDP1KMT2A | |
| SCHEMBL13740300 | 0.81 | CTBP2 (0.47) | CTBP2RAB9AL3MBTL1NPC1HPGD | |
| SCHEMBL13000434 | 0.81 | CTBP2 (0.47) | CTBP2RAB9AL3MBTL1NPC1HPGD | |
| SCHEMBL27275466 | 0.80 | CA2 (0.43) | LMNAGAA | |
| SCHEMBL13727493 | 0.80 | CA2 (0.58) | CTBP2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL7992528 | 0.79 | CTBP2 (0.46) | CTBP2RAB9AL3MBTL1NPC1HPGD | |
| SCHEMBL6451970 | 0.78 | GAA (0.50) | CTBP2RAB9ATDP1KMT2ASMN1; SMN2 | |
| SCHEMBL560200 | 0.78 | TPMT (0.38) | — | |
| SCHEMBL11982003 | 0.78 | CA2 (0.35) | HPGDKMT2AALDH1A1LMNAGAA | |
| SCHEMBL11519547 | 0.78 | NPC1 (0.48) | CTBP2RAB9AL3MBTL1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230024240-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-01-26 | — | — | US | disclosed |
| CN-115286575-A | Quinolinone seven-eight membered ring derivative and synthesis method and application thereof | 河南科技大学 | 2022-11-04 | — | — | CN | disclosed |
| US-20200354384-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2020-11-12 | — | — | US | disclosed |
| US-10626129-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2020-04-21 | — | — | US | disclosed |
| US-20190270759-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2019-09-05 | — | — | US | disclosed |
| US-10364258-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2019-07-30 | — | — | US | disclosed |
| US-20190055269-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2019-02-21 | — | — | US | disclosed |
| US-20160281129-A1 | LUMINESCENT SUBSTRATE FOR USE IN ARTIFICIAL BIOLUMINESCENT ENZYME | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2016-09-29 | — | — | US | disclosed |
| WO-1996035829-A1 | PROCESS FOR THE ELECTROCHEMICAL OXIDATION OF ARYLKETONES | HOECHST CELANESE CORPORATION (US) | 1996-11-14 | — | — | WO | disclosed |
| US-5567299-A | Process for the electrochemical oxidation of arylketones | HOECHST CELANESE CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| US-5500099-A | Process for the electrochemical oxidation of arylketones | HOECHST CELANESE CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| EP-0295547-B1 | Composition curable by photopolymerization | BASF AG (DE) | 1994-06-01 | — | — | EP | disclosed |
| US-4970134-A | Mixture crosslinkable by photopolymerization | BASF AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270759-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
| US-20200354384-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
| US-20230024240-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
| US-20160281129-A1 | LUMINESCENT SUBSTRATE FOR USE IN ARTIFICIAL BIOLUMINESCENT ENZYME | GALC, GUSB, GLB1 | CTBP2 3410/4885RAB9A 3299/4885L3MBTL1 126/4885 |
| US-20190055269-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
| US-10626129-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
| US-10364258-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CTBP2 3668/4885RAB9A 1820/4885L3MBTL1 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.